BDBM50134211 CHEMBL1923492

SMILES: Fc1ccc(Oc2cc(F)cc(\C=C\C#N)c2)c(OCCn2ccc(=O)[nH]c2=O)c1

InChI Key: InChIKey=USRHSVZSPKDGMT-OWOJBTEDSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50134211 (CHEMBL1923492) Show SMILES Fc1ccc(Oc2cc(F)cc(\C=C\C#N)c2)c(OCCn2ccc(=O)[nH]c2=O)c1 Show InChI InChI=1S/C21H15F2N3O4/c22-15-3-4-18(30-17-11-14(2-1-6-24)10-16(23)12-17)19(13-15)29-9-8-26-7-5-20(27)25-21(26)28/h1-5,7,10-13H,8-9H2,(H,25,27,28)/b2-1+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV-1 reverse transcriptase by fluorescence assay				ACS Med Chem Lett 6: 1075-9 (2015) BindingDB Entry DOI: 10.7270/Q2M0479N
					More data for this Ligand-Target Pair