null

SMILES: CN1CC(=O)n2c(cc3ccccc23)C1=O

InChI Key: InChIKey=CGPCCXIXLGOIDA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Geranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50134313 (2-Methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dio...) Show SMILES CN1CC(=O)n2c(cc3ccccc23)C1=O Show InChI InChI=1S/C12H10N2O2/c1-13-7-11(15)14-9-5-3-2-4-8(9)6-10(14)12(13)16/h2-6H,7H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibition of [3H]-GGPP incorporation into recombinant human Ha-Ras-CVLL by Geranylgeranyl transferase type I				Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50134313 (2-Methyl-2,3-dihydro-pyrazino[1,2-a]indole-1,4-dio...) Show SMILES CN1CC(=O)n2c(cc3ccccc23)C1=O Show InChI InChI=1S/C12H10N2O2/c1-13-7-11(15)14-9-5-3-2-4-8(9)6-10(14)12(13)16/h2-6H,7H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College of Science Curated by ChEMBL					Assay Description Inhibition of [3H]-FPP incorporation into recombinant human Ha-Ras-CVLS by farnesyl transferase				Bioorg Med Chem Lett 13: 3661-3 (2003) BindingDB Entry DOI: 10.7270/Q2CF9PHX
					More data for this Ligand-Target Pair