BDBM50134405 CHEMBL421098::N-(4-Carbamimidoyl-benzyl)-2-(5-isopropylamino-3,6-dioxo-2-phenyl-cyclohexa-1,4-dienyl)-acetamide
SMILES: [#6]\[#6](-[#6])=[#7]/c1cc(-[#8])c(-c2ccccc2)c(-[#6]-[#6](=O)-[#7]-[#6]-c2ccc(cc2)-[#6](-[#7])=[#7])c1-[#8]
InChI Key: InChIKey=UBOBFGTVNNSBJS-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (Homo sapiens (Human)) | BDBM50134405 (CHEMBL421098 | N-(4-Carbamimidoyl-benzyl)-2-(5-iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibitory activity of the compound against coagulation factor X | Bioorg Med Chem Lett 13: 3721-5 (2003) BindingDB Entry DOI: 10.7270/Q2QR4WJ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor VII (Homo sapiens (Human)) | BDBM50134405 (CHEMBL421098 | N-(4-Carbamimidoyl-benzyl)-2-(5-iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibitory activity of the compound against tissue coagulation factor VII | Bioorg Med Chem Lett 13: 3721-5 (2003) BindingDB Entry DOI: 10.7270/Q2QR4WJ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50134405 (CHEMBL421098 | N-(4-Carbamimidoyl-benzyl)-2-(5-iso...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Inhibitory activity of the compound against thrombin | Bioorg Med Chem Lett 13: 3721-5 (2003) BindingDB Entry DOI: 10.7270/Q2QR4WJ5 | |||||||||||
More data for this Ligand-Target Pair |