BDBM50134485 CHEMBL3747062

SMILES: OC(=O)C(O)=O.Clc1ccc(OCCCCCCCN2CCCCC2)cc1

InChI Key: InChIKey=JEZMZWXFOXIDPF-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50134485 (CHEMBL3747062) Show SMILES OC(=O)C(O)=O.Clc1ccc(OCCCCCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H28ClNO.C2H2O4/c19-17-9-11-18(12-10-17)21-16-8-3-1-2-5-13-20-14-6-4-7-15-20;3-1(4)2(5)6/h9-12H,1-8,13-16H2;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem 24: 53-72 (2016) BindingDB Entry DOI: 10.7270/Q2NV9M3B
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50134485 (CHEMBL3747062) Show SMILES OC(=O)C(O)=O.Clc1ccc(OCCCCCCCN2CCCCC2)cc1 Show InChI InChI=1S/C18H28ClNO.C2H2O4/c19-17-9-11-18(12-10-17)21-16-8-3-1-2-5-13-20-14-6-4-7-15-20;3-1(4)2(5)6/h9-12H,1-8,13-16H2;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Antagonist activity at human recombinant histamine H3 receptor expressed in HEK293 cells assessed as inhibition of forskolin/(R)(-)-alpha-methylhista...				Bioorg Med Chem 24: 53-72 (2016) BindingDB Entry DOI: 10.7270/Q2NV9M3B
					More data for this Ligand-Target Pair