BDBM50134537 CHEMBL3746056

SMILES: OC(=O)C(O)=O.CC1CCN(CCCCCCOc2ccc(Cl)cc2)CC1

InChI Key: InChIKey=HPSMIHABURGBSB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50134537 (CHEMBL3746056) Show SMILES OC(=O)C(O)=O.CC1CCN(CCCCCCOc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C18H28ClNO.C2H2O4/c1-16-10-13-20(14-11-16)12-4-2-3-5-15-21-18-8-6-17(19)7-9-18;3-1(4)2(5)6/h6-9,16H,2-5,10-15H2,1H3;(H,3,4)(H,5,6)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]-Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK293 cells after 90 mins				Bioorg Med Chem 24: 53-72 (2016) BindingDB Entry DOI: 10.7270/Q2NV9M3B
					More data for this Ligand-Target Pair