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SMILES: O=C1NC(=O)c2c1c1sccc1c1[nH]c3ccccc3c21

InChI Key: InChIKey=NZOGJQDHLOXSKF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134579   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1


(Homo sapiens (Human))		BDBM50134579
PNG
(11H-3-Thia-5,11-diaza-benzo[a]trindene-4,6-dione |...)
Show SMILES O=C1NC(=O)c2c1c1sccc1c1[nH]c3ccccc3c21
Show InChI InChI=1S/C16H8N2O2S/c19-15-11-10-7-3-1-2-4-9(7)17-13(10)8-5-6-21-14(8)12(11)16(20)18-15/h1-6,17H,(H,18,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
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PubMed
n/an/a 150n/an/an/an/an/an/a



Lilly Spain S.A.

Curated by ChEMBL


Assay Description
Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbING

Bioorg Med Chem Lett 13: 3835-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z89BTC
More data for this
Ligand-Target Pair