BDBM50134595 CHEMBL3746969

SMILES: Cn1c2nc(NC3CCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O

InChI Key: InChIKey=MFNOQAZZZQNNRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50134595 (CHEMBL3746969) Show SMILES Cn1c2nc(NC3CCCC3)ncc2cc(Oc2ccc(F)cc2F)c1=O Show InChI InChI=1S/C19H18F2N4O2/c1-25-17-11(10-22-19(24-17)23-13-4-2-3-5-13)8-16(18(25)26)27-15-7-6-12(20)9-14(15)21/h6-10,13H,2-5H2,1H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Semmelweis University Curated by ChEMBL					Assay Description Inhibition of JNK1 (unknown origin)				Bioorg Med Chem Lett 26: 424-8 (2016) BindingDB Entry DOI: 10.7270/Q24T6M6J
					More data for this Ligand-Target Pair