BDBM50134855 4-(6,7-Diethoxy-quinazolin-4-yl)-piperazine-1-carbothioic acid benzylamide::CHEMBL148084

SMILES: CCOc1cc2ncnc(N3CCN(CC3)C(=S)NCc3ccccc3)c2cc1OCC

InChI Key: InChIKey=IOMFDBIBWAGHBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134855   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50134855 (4-(6,7-Diethoxy-quinazolin-4-yl)-piperazine-1-carb...) Show SMILES CCOc1cc2ncnc(N3CCN(CC3)C(=S)NCc3ccccc3)c2cc1OCC Show InChI InChI=1S/C24H29N5O2S/c1-3-30-21-14-19-20(15-22(21)31-4-2)26-17-27-23(19)28-10-12-29(13-11-28)24(32)25-16-18-8-6-5-7-9-18/h5-9,14-15,17H,3-4,10-13,16H2,1-2H3,(H,25,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
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