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SMILES: O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1ncnc2nc[nH]c12

InChI Key: InChIKey=VJQWZMWCEAGZMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134856   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134856
PNG
(4-(9H-Purin-6-yl)-piperazine-1-carboxylic acid (4-...)
Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(CC1)c1ncnc2nc[nH]c12
Show InChI InChI=1S/C22H21N7O2/c30-22(27-16-6-8-18(9-7-16)31-17-4-2-1-3-5-17)29-12-10-28(11-13-29)21-19-20(24-14-23-19)25-15-26-21/h1-9,14-15H,10-13H2,(H,27,30)(H,23,24,25,26)
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Article
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n/an/a 490n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair