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SMILES: CCCCn1c2cc3ncnc(N4CCN(CC4)C(=O)Nc4ccc(Oc5ccccc5)cc4)c3cc2n(CCCC)c1=O

InChI Key: InChIKey=GLDVDHRAIOSBLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134879   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134879
PNG
(4-(1,3-Dibutyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-g]...)
Show SMILES CCCCn1c2cc3ncnc(N4CCN(CC4)C(=O)Nc4ccc(Oc5ccccc5)cc4)c3cc2n(CCCC)c1=O
Show InChI InChI=1S/C34H39N7O3/c1-3-5-16-40-30-22-28-29(23-31(30)41(34(40)43)17-6-4-2)35-24-36-32(28)38-18-20-39(21-19-38)33(42)37-25-12-14-27(15-13-25)44-26-10-8-7-9-11-26/h7-15,22-24H,3-6,16-21H2,1-2H3,(H,37,42)
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair