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SMILES: CCCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC

InChI Key: InChIKey=JGDYKGMYFGQGDI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134891   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))		BDBM50134891
PNG
(4-(7-Butoxy-6-methoxy-quinazolin-4-yl)-piperazine-...)
Show SMILES CCCCOc1cc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC
Show InChI InChI=1S/C30H33N5O4/c1-3-4-18-38-28-20-26-25(19-27(28)37-2)29(32-21-31-26)34-14-16-35(17-15-34)30(36)33-22-10-12-24(13-11-22)39-23-8-6-5-7-9-23/h5-13,19-21H,3-4,14-18H2,1-2H3,(H,33,36)
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Article
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n/an/a 650n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...

J Med Chem 46: 4910-25 (2003)


Article DOI: 10.1021/jm020505v
BindingDB Entry DOI: 10.7270/Q2X929PJ
More data for this
Ligand-Target Pair