BDBM50135025 1-(5-hydroxy-2-(2-hydroxy-3-(piperidin-1-yl)propoxy)phenyl)-3-phenylpropan-1-one::1-[5-Hydroxy-2-(2-hydroxy-3-piperidin-1-yl-propoxy)-phenyl]-3-phenyl-propan-1-one::CHEMBL148196

SMILES: OC(COc1ccc(O)cc1C(=O)CCc1ccccc1)CN1CCCCC1

InChI Key: InChIKey=HNTYJJIDGXCTPP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50135025 (1-(5-hydroxy-2-(2-hydroxy-3-(piperidin-1-yl)propox...) Show SMILES OC(COc1ccc(O)cc1C(=O)CCc1ccccc1)CN1CCCCC1 Show InChI InChI=1S/C23H29NO4/c25-19-10-12-23(28-17-20(26)16-24-13-5-2-6-14-24)21(15-19)22(27)11-9-18-7-3-1-4-8-18/h1,3-4,7-8,10,12,15,20,25-26H,2,5-6,9,11,13-14,16-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a
University of Vienna Curated by ChEMBL					Assay Description Inhibition of P-glycoprotein expressed in MDR CCRF vcr1000 cells by daunorubicin efflux assay				J Med Chem 50: 1698-702 (2007) Article DOI: 10.1021/jm060604z BindingDB Entry DOI: 10.7270/Q2SB46JC
					More data for this Ligand-Target Pair