BDBM50135054 CHEMBL344507::Compound 9.35::[(2-Cyclopentylamino-acetylamino)-phenyl-methyl]-phosphonic acid diphenyl ester

SMILES: O=C(CNC1CCCC1)NC(c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1

InChI Key: InChIKey=KMXSJSIRHCXWKV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50135054 (CHEMBL344507 | Compound 9.35 | [(2-Cyclopentylamin...) Show SMILES O=C(CNC1CCCC1)NC(c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1 Show InChI InChI=1S/C26H29N2O4P/c29-25(20-27-22-14-10-11-15-22)28-26(21-12-4-1-5-13-21)33(30,31-23-16-6-2-7-17-23)32-24-18-8-3-9-19-24/h1-9,12-13,16-19,22,26-27H,10-11,14-15,20H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	8.3	0
University of Anterwerp					Assay Description Inhibitory concentration of the compound against Dipeptidyl peptidase IV (DPP IV) in Homo sapiens (human)is measured				J Comb Chem 5: 336-44 (2003) Article DOI: 10.1021/cc020096o BindingDB Entry DOI: 10.7270/Q2PV6J1S
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50135054 (CHEMBL344507 | Compound 9.35 | [(2-Cyclopentylamin...) Show SMILES O=C(CNC1CCCC1)NC(c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1 Show InChI InChI=1S/C26H29N2O4P/c29-25(20-27-22-14-10-11-15-22)28-26(21-12-4-1-5-13-21)33(30,31-23-16-6-2-7-17-23)32-24-18-8-3-9-19-24/h1-9,12-13,16-19,22,26-27H,10-11,14-15,20H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV)				J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50135054 (CHEMBL344507 | Compound 9.35 | [(2-Cyclopentylamin...) Show SMILES O=C(CNC1CCCC1)NC(c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1 Show InChI InChI=1S/C26H29N2O4P/c29-25(20-27-22-14-10-11-15-22)28-26(21-12-4-1-5-13-21)33(30,31-23-16-6-2-7-17-23)32-24-18-8-3-9-19-24/h1-9,12-13,16-19,22,26-27H,10-11,14-15,20H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Antwerp (UIA) Curated by ChEMBL					Assay Description Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II)				J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50135054 (CHEMBL344507 | Compound 9.35 | [(2-Cyclopentylamin...) Show SMILES O=C(CNC1CCCC1)NC(c1ccccc1)P(=O)(Oc1ccccc1)Oc1ccccc1 Show InChI InChI=1S/C26H29N2O4P/c29-25(20-27-22-14-10-11-15-22)28-26(21-12-4-1-5-13-21)33(30,31-23-16-6-2-7-17-23)32-24-18-8-3-9-19-24/h1-9,12-13,16-19,22,26-27H,10-11,14-15,20H2,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	5.5	0
University of Anterwerp					Assay Description Inhibitory concentration of the compound against Dipeptidyl peptidase IV (DPP IV) in Homo sapiens (human)is measured				J Comb Chem 5: 336-44 (2003) Article DOI: 10.1021/cc020096o BindingDB Entry DOI: 10.7270/Q2PV6J1S
					More data for this Ligand-Target Pair