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BDBM50135115 CHEMBL3741066

SMILES: CCCOc1nccc2c(n[nH]c12)-c1cnc(s1)-c1ccc(CO)nc1

InChI Key: InChIKey=AHCCZFIPLMGFCL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135115   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA gyrase


(Staphylococcus aureus)
BDBM50135115
PNG
(CHEMBL3741066)
Show SMILES CCCOc1nccc2c(n[nH]c12)-c1cnc(s1)-c1ccc(CO)nc1
Show InChI InChI=1S/C18H17N5O2S/c1-2-7-25-17-16-13(5-6-19-17)15(22-23-16)14-9-21-18(26-14)11-3-4-12(10-24)20-8-11/h3-6,8-9,24H,2,7,10H2,1H3,(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a<8n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Gyrase B ATPase activity by fluorescence analysis


ACS Med Chem Lett 6: 1080-5 (2015)


BindingDB Entry DOI: 10.7270/Q2GB25VF
More data for this
Ligand-Target Pair