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SMILES: CCCOc1nccc2c(n[nH]c12)-c1cnc(s1)-c1ccc(nc1)C(O)=O

InChI Key: InChIKey=HDCNADZRFBRBAY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135116   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Staphylococcus aureus)		BDBM50135116
PNG
(CHEMBL3740365)
Show SMILES CCCOc1nccc2c(n[nH]c12)-c1cnc(s1)-c1ccc(nc1)C(O)=O
Show InChI InChI=1S/C18H15N5O3S/c1-2-7-26-16-15-11(5-6-19-16)14(22-23-15)13-9-21-17(27-13)10-3-4-12(18(24)25)20-8-10/h3-6,8-9H,2,7H2,1H3,(H,22,23)(H,24,25)
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PubMed
n/an/a<8n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus Gyrase B ATPase activity by fluorescence analysis

ACS Med Chem Lett 6: 1080-5 (2015)


BindingDB Entry DOI: 10.7270/Q2GB25VF
More data for this
Ligand-Target Pair