BDBM50135174 CHEMBL3747431

SMILES: Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O

InChI Key: InChIKey=AQSOTOUQTVJNMY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dickkopf-related protein 1 (Mus musculus)	BDBM50135174 (CHEMBL3747431) Show SMILES Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O Show InChI InChI=1S/C15H12N2O5.ClH/c1-17(2)7-3-4-9-11(5-7)22-14-12(16-9)8(15(20)21)6-10(18)13(14)19;/h3-6,19H,1-2H3,(H,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Inhibition of mouse DKK1 assessed as inhibition of DKK1-alkaline phophatase binding to LRP5 transfected in HEK293 cells				Eur J Med Chem 108: 28-38 (2016) BindingDB Entry DOI: 10.7270/Q2TF0067
					More data for this Ligand-Target Pair
Low-density lipoprotein receptor-related protein 6 (Homo sapiens (Human))	BDBM50135174 (CHEMBL3747431) Show SMILES Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O Show InChI InChI=1S/C15H12N2O5.ClH/c1-17(2)7-3-4-9-11(5-7)22-14-12(16-9)8(15(20)21)6-10(18)13(14)19;/h3-6,19H,1-2H3,(H,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...				Bioorg Med Chem 24: 1014-22 (2016) BindingDB Entry DOI: 10.7270/Q2J67JRS
					More data for this Ligand-Target Pair
Low-density lipoprotein receptor-related protein 6 (Homo sapiens (Human))	BDBM50135174 (CHEMBL3747431) Show SMILES Cl.CN(C)c1ccc2nc3c(cc(=O)c(O)c3oc2c1)C(O)=O Show InChI InChI=1S/C15H12N2O5.ClH/c1-17(2)7-3-4-9-11(5-7)22-14-12(16-9)8(15(20)21)6-10(18)13(14)19;/h3-6,19H,1-2H3,(H,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...				Bioorg Med Chem 24: 1014-22 (2016) BindingDB Entry DOI: 10.7270/Q2J67JRS
					More data for this Ligand-Target Pair