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SMILES: CN(C)C(=O)CNC(=O)c1cn(Cc2ccc(cc2)-n2cccn2)c2cccnc12

InChI Key: InChIKey=FVRDVPWXXJTFKT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135200   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50135200
PNG
(CHEMBL3746514)
Show SMILES CN(C)C(=O)CNC(=O)c1cn(Cc2ccc(cc2)-n2cccn2)c2cccnc12
Show InChI InChI=1S/C22H22N6O2/c1-26(2)20(29)13-24-22(30)18-15-27(19-5-3-10-23-21(18)19)14-16-6-8-17(9-7-16)28-12-4-11-25-28/h3-12,15H,13-14H2,1-2H3,(H,24,30)
UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/an/an/a 112n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 26: 650-5 (2016)


BindingDB Entry DOI: 10.7270/Q29C708F
More data for this
Ligand-Target Pair