BDBM50135206 CHEMBL3747724

SMILES: Cn1ccc(NC(=O)c2cn(Cc3ccc(cc3)-n3cccn3)c3cccnc23)n1

InChI Key: InChIKey=DHRDIENMVNDVSW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135206   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50135206 (CHEMBL3747724) Show SMILES Cn1ccc(NC(=O)c2cn(Cc3ccc(cc3)-n3cccn3)c3cccnc23)n1 Show InChI InChI=1S/C22H19N7O/c1-27-13-9-20(26-27)25-22(30)18-15-28(19-4-2-10-23-21(18)19)14-16-5-7-17(8-6-16)29-12-3-11-24-29/h2-13,15H,14H2,1H3,(H,25,26,30)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	258	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 26: 650-5 (2016) BindingDB Entry DOI: 10.7270/Q29C708F
					More data for this Ligand-Target Pair