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BDBM50135207 CHEMBL3747287

SMILES: OC1(CNC(=O)c2cn(Cc3ccc(cc3)-n3cccn3)c3cccnc23)CCC1

InChI Key: InChIKey=UBLVCMJAWALPPL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135207   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50135207
PNG
(CHEMBL3747287)
Show SMILES OC1(CNC(=O)c2cn(Cc3ccc(cc3)-n3cccn3)c3cccnc23)CCC1
Show InChI InChI=1S/C23H23N5O2/c29-22(25-16-23(30)9-2-10-23)19-15-27(20-4-1-11-24-21(19)20)14-17-5-7-18(8-6-17)28-13-3-12-26-28/h1,3-8,11-13,15,30H,2,9-10,14,16H2,(H,25,29)
UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/an/an/a 500n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 26: 650-5 (2016)


BindingDB Entry DOI: 10.7270/Q29C708F
More data for this
Ligand-Target Pair