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BDBM50135210 CHEMBL3746104

SMILES: O[C@H]1CCCC[C@@H]1NC(=O)c1nn(Cc2ccc(cc2)-n2cccn2)c2cccnc12

InChI Key: InChIKey=LZSDKRWJHHWPBL-ICSRJNTNSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135210   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50135210
PNG
(CHEMBL3746104)
Show SMILES O[C@H]1CCCC[C@@H]1NC(=O)c1nn(Cc2ccc(cc2)-n2cccn2)c2cccnc12 |r|
Show InChI InChI=1S/C23H24N6O2/c30-20-7-2-1-5-18(20)26-23(31)22-21-19(6-3-12-24-21)29(27-22)15-16-8-10-17(11-9-16)28-14-4-13-25-28/h3-4,6,8-14,18,20,30H,1-2,5,7,15H2,(H,26,31)/t18-,20-/m0/s1
UniProtKB/SwissProt
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/an/an/a 215n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 26: 650-5 (2016)


BindingDB Entry DOI: 10.7270/Q29C708F
More data for this
Ligand-Target Pair