BDBM50135228 CHEMBL3746729
SMILES: COc1ccc(cc1)S(=O)(=O)N(Nc1ccccc1)C(=O)Oc1ccc2CCCc2c1
InChI Key: InChIKey=DAWFRGFGIAQWKS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50135228 (CHEMBL3746729) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University Curated by ChEMBL | Assay Description Inhibition of PGES-1 in human A549 cell microsomes using PGH2 as substrate assessed as suppression of interleukin-1beta-stimulated PGE2 production in... | Bioorg Med Chem Lett 26: 94-9 (2015) BindingDB Entry DOI: 10.7270/Q2PR7XT0 | |||||||||||
More data for this Ligand-Target Pair |