BDBM50135563 4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy}-phthalic acid::CHEMBL132201

SMILES: OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O

InChI Key: InChIKey=KWAQGJBZAIHRQW-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen phosphorylase, liver form (Homo sapiens (Human))	BDBM50135563 (4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy...) Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O Show InChI InChI=1S/C21H13N3O6/c22-11-12-7-8-23-17(9-12)19(25)24-16-3-1-2-4-18(16)30-13-5-6-14(20(26)27)15(10-13)21(28)29/h1-10H,(H,24,25)(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HLGP(human liver glycogen phosphorylase)				Bioorg Med Chem Lett 13: 4125-8 (2003) BindingDB Entry DOI: 10.7270/Q26M367F
					More data for this Ligand-Target Pair
Glycogen phosphorylase, muscle form (Homo sapiens (Human))	BDBM50135563 (4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy...) Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O Show InChI InChI=1S/C21H13N3O6/c22-11-12-7-8-23-17(9-12)19(25)24-16-3-1-2-4-18(16)30-13-5-6-14(20(26)27)15(10-13)21(28)29/h1-10H,(H,24,25)(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against HMGP(human muscle glycogen phosphorylase)				Bioorg Med Chem Lett 13: 4125-8 (2003) BindingDB Entry DOI: 10.7270/Q26M367F
					More data for this Ligand-Target Pair
Glycogen phosphorylase, liver form (Rattus norvegicus)	BDBM50135563 (4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy...) Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O Show InChI InChI=1S/C21H13N3O6/c22-11-12-7-8-23-17(9-12)19(25)24-16-3-1-2-4-18(16)30-13-5-6-14(20(26)27)15(10-13)21(28)29/h1-10H,(H,24,25)(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against rat liver glycogen phosphorylase				Bioorg Med Chem Lett 13: 4125-8 (2003) BindingDB Entry DOI: 10.7270/Q26M367F
					More data for this Ligand-Target Pair
Glycogen phosphorylase, liver form (Mus musculus)	BDBM50135563 (4-{2-[(4-Cyano-pyridine-2-carbonyl)-amino]-phenoxy...) Show SMILES OC(=O)c1ccc(Oc2ccccc2NC(=O)c2cc(ccn2)C#N)cc1C(O)=O Show InChI InChI=1S/C21H13N3O6/c22-11-12-7-8-23-17(9-12)19(25)24-16-3-1-2-4-18(16)30-13-5-6-14(20(26)27)15(10-13)21(28)29/h1-10H,(H,24,25)(H,26,27)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against mouse liver glycogen phosphorylase				Bioorg Med Chem Lett 13: 4125-8 (2003) BindingDB Entry DOI: 10.7270/Q26M367F
					More data for this Ligand-Target Pair