BDBM50135781 2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propyl-4,5-dihydro-1H-[1,2,4]triazol-3-yl]-propyl}-phenoxy)-propionic acid::CHEMBL356170

SMILES: CCCn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(C(C)c2ccccc2)c1=O

InChI Key: InChIKey=JPZWIGDPGASOSL-UHFFFAOYSA-N

Data: 3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50135781 (2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...) Show SMILES CCCn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(C(C)c2ccccc2)c1=O Show InChI InChI=1S/C26H33N3O4/c1-5-18-28-23(27-29(25(28)32)19(2)21-11-7-6-8-12-21)13-9-10-20-14-16-22(17-15-20)33-26(3,4)24(30)31/h6-8,11-12,14-17,19H,5,9-10,13,18H2,1-4H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Cotransfection activity against human Peroxisome proliferator activated receptor alpha				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50135781 (2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...) Show SMILES CCCn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(C(C)c2ccccc2)c1=O Show InChI InChI=1S/C26H33N3O4/c1-5-18-28-23(27-29(25(28)32)19(2)21-11-7-6-8-12-21)13-9-10-20-14-16-22(17-15-20)33-26(3,4)24(30)31/h6-8,11-12,14-17,19H,5,9-10,13,18H2,1-4H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity against human Peroxisome proliferator activated receptor alpha				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50135781 (2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...) Show SMILES CCCn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(C(C)c2ccccc2)c1=O Show InChI InChI=1S/C26H33N3O4/c1-5-18-28-23(27-29(25(28)32)19(2)21-11-7-6-8-12-21)13-9-10-20-14-16-22(17-15-20)33-26(3,4)24(30)31/h6-8,11-12,14-17,19H,5,9-10,13,18H2,1-4H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor gamma was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50135781 (2-Methyl-2-(4-{3-[5-oxo-1-(1-phenyl-ethyl)-4-propy...) Show SMILES CCCn1c(CCCc2ccc(OC(C)(C)C(O)=O)cc2)nn(C(C)c2ccccc2)c1=O Show InChI InChI=1S/C26H33N3O4/c1-5-18-28-23(27-29(25(28)32)19(2)21-11-7-6-8-12-21)13-9-10-20-14-16-22(17-15-20)33-26(3,4)24(30)31/h6-8,11-12,14-17,19H,5,9-10,13,18H2,1-4H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory activity of compound against the binding of human Peroxisome proliferator activated receptor delta was determined				J Med Chem 46: 5121-4 (2003) Article DOI: 10.1021/jm034173l BindingDB Entry DOI: 10.7270/Q2D50MB0
					More data for this Ligand-Target Pair