BDBM50135944 2-(4-Hydroxy-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL358488

SMILES: Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc(O)cc1

InChI Key: InChIKey=OUCSIVJSDQZNMB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135944   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50135944 (2-(4-Hydroxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc(O)cc1 Show InChI InChI=1S/C23H20N4O4S/c1-15-14-21(27(26-15)18-10-12-19(28)13-11-18)23(29)25-17-8-6-16(7-9-17)20-4-2-3-5-22(20)32(24,30)31/h2-14,28H,1H3,(H,25,29)(H2,24,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Tested in vitro for inhibition of human Coagulation factor X				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50135944 (2-(4-Hydroxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc(O)cc1 Show InChI InChI=1S/C23H20N4O4S/c1-15-14-21(27(26-15)18-10-12-19(28)13-11-18)23(29)25-17-8-6-16(7-9-17)20-4-2-3-5-22(20)32(24,30)31/h2-14,28H,1H3,(H,25,29)(H2,24,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Tested in vitro for inhibition of human trypsin				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50135944 (2-(4-Hydroxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2)-c2ccccc2S(N)(=O)=O)n(n1)-c1ccc(O)cc1 Show InChI InChI=1S/C23H20N4O4S/c1-15-14-21(27(26-15)18-10-12-19(28)13-11-18)23(29)25-17-8-6-16(7-9-17)20-4-2-3-5-22(20)32(24,30)31/h2-14,28H,1H3,(H,25,29)(H2,24,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro for inhibition of human thrombin				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair