BDBM50135965 2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL147132

SMILES: COc1ccc(cc1)-n1nc(C)cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=JSJQUUOZSGSQMO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50135965 (2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES COc1ccc(cc1)-n1nc(C)cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C24H21FN4O4S/c1-15-13-22(29(28-15)17-8-10-18(33-2)11-9-17)24(30)27-21-12-7-16(14-20(21)25)19-5-3-4-6-23(19)34(26,31)32/h3-14H,1-2H3,(H,27,30)(H2,26,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Tested in vitro for inhibition of human Coagulation factor X				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair
Trypsin-1 (Homo sapiens (Human))	BDBM50135965 (2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES COc1ccc(cc1)-n1nc(C)cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C24H21FN4O4S/c1-15-13-22(29(28-15)17-8-10-18(33-2)11-9-17)24(30)27-21-12-7-16(14-20(21)25)19-5-3-4-6-23(19)34(26,31)32/h3-14H,1-2H3,(H,27,30)(H2,26,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Tested in vitro for inhibition of human trypsin				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50135965 (2-(4-Methoxy-phenyl)-5-methyl-2H-pyrazole-3-carbox...) Show SMILES COc1ccc(cc1)-n1nc(C)cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O Show InChI InChI=1S/C24H21FN4O4S/c1-15-13-22(29(28-15)17-8-10-18(33-2)11-9-17)24(30)27-21-12-7-16(14-20(21)25)19-5-3-4-6-23(19)34(26,31)32/h3-14H,1-2H3,(H,27,30)(H2,26,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro for inhibition of human thrombin				J Med Chem 46: 5298-315 (2003) Article DOI: 10.1021/jm030212h BindingDB Entry DOI: 10.7270/Q2ZW1MP2
					More data for this Ligand-Target Pair