BDBM50136221 CHEMBL3754734

SMILES: O=C(COc1ccc(cc1)C1=NCCN1)Nc1ccccc1

InChI Key: InChIKey=VHHJMPXCBTTZEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CviR transcriptional regulator (Chromobacterium violaceum)	BDBM50136221 (CHEMBL3754734) Show SMILES O=C(COc1ccc(cc1)C1=NCCN1)Nc1ccccc1 |t:11| Show InChI InChI=1S/C17H17N3O2/c21-16(20-14-4-2-1-3-5-14)12-22-15-8-6-13(7-9-15)17-18-10-11-19-17/h1-9H,10-12H2,(H,18,19)(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.61E+4	n/a	n/a	n/a	n/a	n/a	n/a
Instituto Polit£cnico Nacional Curated by ChEMBL					Assay Description Inhibition of CviR in Chromobacterium violaceum CV026 assessed as reduction of violacein production after 15 hrs				Bioorg Med Chem 23: 7565-77 (2015) BindingDB Entry DOI: 10.7270/Q2RF5WVS
					More data for this Ligand-Target Pair