BDBM50136257 (1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[(4-benzyloxy-phenyl)-amide] 2-hydroxyamide::CHEMBL137406

SMILES: ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=PYZZBYJLLRVFDM-OALUTQOASA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50136257 ((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[(4-be...) Show SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H24N2O4/c24-20(18-8-4-5-9-19(18)21(25)23-26)22-16-10-12-17(13-11-16)27-14-15-6-2-1-3-7-15/h1-3,6-7,10-13,18-19,26H,4-5,8-9,14H2,(H,22,24)(H,23,25)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-9(MMP-9)				Bioorg Med Chem Lett 13: 4293-7 (2003) BindingDB Entry DOI: 10.7270/Q2T72GV7
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50136257 ((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[(4-be...) Show SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H24N2O4/c24-20(18-8-4-5-9-19(18)21(25)23-26)22-16-10-12-17(13-11-16)27-14-15-6-2-1-3-7-15/h1-3,6-7,10-13,18-19,26H,4-5,8-9,14H2,(H,22,24)(H,23,25)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-2(MMP-2)				Bioorg Med Chem Lett 13: 4293-7 (2003) BindingDB Entry DOI: 10.7270/Q2T72GV7
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50136257 ((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[(4-be...) Show SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H24N2O4/c24-20(18-8-4-5-9-19(18)21(25)23-26)22-16-10-12-17(13-11-16)27-14-15-6-2-1-3-7-15/h1-3,6-7,10-13,18-19,26H,4-5,8-9,14H2,(H,22,24)(H,23,25)/t18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>4.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of matrix metalloproteinase-1(MMP-1)				Bioorg Med Chem Lett 13: 4293-7 (2003) BindingDB Entry DOI: 10.7270/Q2T72GV7
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Sus scrofa (pig))	BDBM50136257 ((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-[(4-be...) Show SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(OCc2ccccc2)cc1 Show InChI InChI=1S/C21H24N2O4/c24-20(18-8-4-5-9-19(18)21(25)23-26)22-16-10-12-17(13-11-16)27-14-15-6-2-1-3-7-15/h1-3,6-7,10-13,18-19,26H,4-5,8-9,14H2,(H,22,24)(H,23,25)/t18-,19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of porcine TACE				Bioorg Med Chem Lett 13: 4293-7 (2003) BindingDB Entry DOI: 10.7270/Q2T72GV7
					More data for this Ligand-Target Pair