BDBM50136444 5-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-amide::CHEMBL342364

SMILES: CN1c2ccccc2CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1=O

InChI Key: InChIKey=HRRVJTJSCYCYMB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM50136444 (5-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...) Show SMILES CN1c2ccccc2CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1=O Show InChI InChI=1S/C20H18ClN3O2/c1-24-18-5-3-2-4-12(18)6-8-16(20(24)26)23-19(25)17-11-13-10-14(21)7-9-15(13)22-17/h2-5,7,9-11,16,22H,6,8H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human muscle glycogen phosphorylase a (HMGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136444 (5-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...) Show SMILES CN1c2ccccc2CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1=O Show InChI InChI=1S/C20H18ClN3O2/c1-24-18-5-3-2-4-12(18)6-8-16(20(24)26)23-19(25)17-11-13-10-14(21)7-9-15(13)22-17/h2-5,7,9-11,16,22H,6,8H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Applied Science University Curated by ChEMBL					Assay Description Inhibition of human liver glycogen phosphorylase 1a assessed as release of phosphate from glucose-1- phosphate after 20 mins				Bioorg Med Chem 19: 4746-71 (2011) Article DOI: 10.1016/j.bmc.2011.06.086 BindingDB Entry DOI: 10.7270/Q2028RXJ
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50136444 (5-Chloro-1H-indole-2-carboxylic acid (1-methyl-2-o...) Show SMILES CN1c2ccccc2CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C1=O Show InChI InChI=1S/C20H18ClN3O2/c1-24-18-5-3-2-4-12(18)6-8-16(20(24)26)23-19(25)17-11-13-10-14(21)7-9-15(13)22-17/h2-5,7,9-11,16,22H,6,8H2,1H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	305	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human liver glycogen phosphorylase a (HLGPa)				Bioorg Med Chem Lett 13: 4385-8 (2003) BindingDB Entry DOI: 10.7270/Q2S75FQV
					More data for this Ligand-Target Pair