BDBM50136633 CHEMBL3754680

SMILES: CN(C)C[C@@H]1CC[C@@H](N1S(=O)(=O)c1cc(C)c(F)c(C)c1)c1ccc(F)cc1

InChI Key: InChIKey=WLXHLHFIWPSBNX-AZUAARDMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136633   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Homo sapiens (Human))	BDBM50136633 (CHEMBL3754680) Show SMILES CN(C)C[C@@H]1CC[C@@H](N1S(=O)(=O)c1cc(C)c(F)c(C)c1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C21H26F2N2O2S/c1-14-11-19(12-15(2)21(14)23)28(26,27)25-18(13-24(3)4)9-10-20(25)16-5-7-17(22)8-6-16/h5-8,11-12,18,20H,9-10,13H2,1-4H3/t18-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of human TRPA1				Bioorg Med Chem Lett 26: 495-8 (2016) BindingDB Entry DOI: 10.7270/Q23R0VRB
					More data for this Ligand-Target Pair