BDBM50136678 CHEMBL337798::[3-(3-Bromo-phenyl)-3-(naphthalen-1-yloxy)-propyl]-methyl-amine
SMILES: CNCCC(Oc1cccc2ccccc12)c1cccc(Br)c1
InChI Key: InChIKey=UKLJVQPVIADCAE-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50136678 (CHEMBL337798 | [3-(3-Bromo-phenyl)-3-(naphthalen-1...) | PDB KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Binding affinity to serotonin transporter, using [3H]-citalopram as radioligand | Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50136678 (CHEMBL337798 | [3-(3-Bromo-phenyl)-3-(naphthalen-1...) | Reactome pathway KEGG DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Inhibition of [3H]-nisoxatine binding to norepinephrine (NE) transporter | Bioorg Med Chem Lett 13: 4477-80 (2003) BindingDB Entry DOI: 10.7270/Q24J0DJH | |||||||||||
More data for this Ligand-Target Pair |