BDBM50136722 4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-methoxy-benzoic acid::CHEMBL140539
SMILES: COc1cc(ccc1Cc1cn(C(c2ccccc2)c2ccccc2)c2ccc(Br)cc12)C(O)=O
InChI Key: InChIKey=FECNHWUMLHYCRX-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cPLA2 C2 (Homo sapiens (Human)) | BDBM50136722 (4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against cystolic phospholipase A2 alpha receptor (c-PLA2 alpha) using coumarin assay | Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50136722 (4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against LTB4 receptor determined in mast cell line MC-9 assay | Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leukotriene B4 receptor (Homo sapiens (Human)) | BDBM50136722 (4-(1-Benzhydryl-5-bromo-1H-indol-3-ylmethyl)-3-met...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against LTB4 receptor determined in human neutrophils PMN assay | Bioorg Med Chem Lett 13: 4501-4 (2003) BindingDB Entry DOI: 10.7270/Q2W095BN | |||||||||||
More data for this Ligand-Target Pair |