BDBM50136810 CHEMBL406815::Somatostatin analogue

SMILES: C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1

InChI Key: InChIKey=OKHBWYBPTMVZRR-KIGUQPRQSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50136810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50136810 (CHEMBL406815 | Somatostatin analogue) Show SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C57H71N11O12S2/c1-32-49(71)63-45(28-37-29-60-41-18-10-9-17-39(37)41)54(76)62-42(19-11-12-24-58)51(73)68-48(33(2)69)56(78)65-44(27-35-15-7-4-8-16-35)53(75)67-47(57(79)80)31-82-81-30-46(66-50(72)40(59)25-36-20-22-38(70)23-21-36)55(77)64-43(52(74)61-32)26-34-13-5-3-6-14-34/h3-10,13-18,20-23,29,32-33,40,42-48,60,69-70H,11-12,19,24-28,30-31,58-59H2,1-2H3,(H,61,74)(H,62,76)(H,63,71)(H,64,77)(H,65,78)(H,66,72)(H,67,75)(H,68,73)(H,79,80)/t32-,33+,40+,42-,43+,44-,45+,46+,47-,48+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 3 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50136810 (CHEMBL406815 | Somatostatin analogue) Show SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C57H71N11O12S2/c1-32-49(71)63-45(28-37-29-60-41-18-10-9-17-39(37)41)54(76)62-42(19-11-12-24-58)51(73)68-48(33(2)69)56(78)65-44(27-35-15-7-4-8-16-35)53(75)67-47(57(79)80)31-82-81-30-46(66-50(72)40(59)25-36-20-22-38(70)23-21-36)55(77)64-43(52(74)61-32)26-34-13-5-3-6-14-34/h3-10,13-18,20-23,29,32-33,40,42-48,60,69-70H,11-12,19,24-28,30-31,58-59H2,1-2H3,(H,61,74)(H,62,76)(H,63,71)(H,64,77)(H,65,78)(H,66,72)(H,67,75)(H,68,73)(H,79,80)/t32-,33+,40+,42-,43+,44-,45+,46+,47-,48+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 5 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 4 (Homo sapiens (Human))	BDBM50136810 (CHEMBL406815 | Somatostatin analogue) Show SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C57H71N11O12S2/c1-32-49(71)63-45(28-37-29-60-41-18-10-9-17-39(37)41)54(76)62-42(19-11-12-24-58)51(73)68-48(33(2)69)56(78)65-44(27-35-15-7-4-8-16-35)53(75)67-47(57(79)80)31-82-81-30-46(66-50(72)40(59)25-36-20-22-38(70)23-21-36)55(77)64-43(52(74)61-32)26-34-13-5-3-6-14-34/h3-10,13-18,20-23,29,32-33,40,42-48,60,69-70H,11-12,19,24-28,30-31,58-59H2,1-2H3,(H,61,74)(H,62,76)(H,63,71)(H,64,77)(H,65,78)(H,66,72)(H,67,75)(H,68,73)(H,79,80)/t32-,33+,40+,42-,43+,44-,45+,46+,47-,48+/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 4 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 1 (Homo sapiens (Human))	BDBM50136810 (CHEMBL406815 | Somatostatin analogue) Show SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C57H71N11O12S2/c1-32-49(71)63-45(28-37-29-60-41-18-10-9-17-39(37)41)54(76)62-42(19-11-12-24-58)51(73)68-48(33(2)69)56(78)65-44(27-35-15-7-4-8-16-35)53(75)67-47(57(79)80)31-82-81-30-46(66-50(72)40(59)25-36-20-22-38(70)23-21-36)55(77)64-43(52(74)61-32)26-34-13-5-3-6-14-34/h3-10,13-18,20-23,29,32-33,40,42-48,60,69-70H,11-12,19,24-28,30-31,58-59H2,1-2H3,(H,61,74)(H,62,76)(H,63,71)(H,64,77)(H,65,78)(H,66,72)(H,67,75)(H,68,73)(H,79,80)/t32-,33+,40+,42-,43+,44-,45+,46+,47-,48+/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 1 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair
Somatostatin receptor type 2 (Homo sapiens (Human))	BDBM50136810 (CHEMBL406815 | Somatostatin analogue) Show SMILES C[C@@H](O)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)C(O)=O)NC(=O)[C@H](N)Cc1ccc(O)cc1 Show InChI InChI=1S/C57H71N11O12S2/c1-32-49(71)63-45(28-37-29-60-41-18-10-9-17-39(37)41)54(76)62-42(19-11-12-24-58)51(73)68-48(33(2)69)56(78)65-44(27-35-15-7-4-8-16-35)53(75)67-47(57(79)80)31-82-81-30-46(66-50(72)40(59)25-36-20-22-38(70)23-21-36)55(77)64-43(52(74)61-32)26-34-13-5-3-6-14-34/h3-10,13-18,20-23,29,32-33,40,42-48,60,69-70H,11-12,19,24-28,30-31,58-59H2,1-2H3,(H,61,74)(H,62,76)(H,63,71)(H,64,77)(H,65,78)(H,66,72)(H,67,75)(H,68,73)(H,79,80)/t32-,33+,40+,42-,43+,44-,45+,46+,47-,48+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Salk Institute Curated by ChEMBL					Assay Description Binding affinity towards human somatostatin receptor type 2 using [125I]-[Leu8,DTrp22,Tyr25]SRIF-28 as radioligand.				J Med Chem 46: 5597-605 (2003) Article DOI: 10.1021/jm030245x BindingDB Entry DOI: 10.7270/Q2MK6C9X
					More data for this Ligand-Target Pair