BDBM50136931 4-Chloro-N-[3-chloro-7-(2,2-dimethyl-propylamino)-1H-indazol-5-yl]-benzenesulfonamide::CHEMBL435874

SMILES: CC(C)(C)CNc1cc(NS(=O)(=O)c2ccc(Cl)cc2)cc2c(Cl)[nH]nc12

InChI Key: InChIKey=OOQBBAVUQUYUQX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136931   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methylthioadenosine Nucleosidase(MTAN) (Escherichia coli (strain K12))	BDBM50136931 (4-Chloro-N-[3-chloro-7-(2,2-dimethyl-propylamino)-...) Show SMILES CC(C)(C)CNc1cc(NS(=O)(=O)c2ccc(Cl)cc2)cc2c(Cl)[nH]nc12 Show InChI InChI=1S/C18H20Cl2N4O2S/c1-18(2,3)10-21-15-9-12(8-14-16(15)22-23-17(14)20)24-27(25,26)13-6-4-11(19)5-7-13/h4-9,21,24H,10H2,1-3H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Quorex Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)				J Med Chem 46: 5663-73 (2003) Article DOI: 10.1021/jm0302039 BindingDB Entry DOI: 10.7270/Q279443D
					More data for this Ligand-Target Pair