BDBM50137098 1-(7-Acetylamino-5,8-dioxo-5,8-dihydro-quinolin-2-yl)-4-methyl-9H-beta-carboline-3-carboxylic acid methyl ester::CHEMBL347211::methyl 1-(7-acetamido-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-methyl-9H-pyrido[3,4-b]indole-3-carboxylate

SMILES: COC(=O)c1[nH]c(-c2ccc3C(=O)C=C(NC(C)=O)C(=O)c3n2)c2nc3ccccc3c2c1C

InChI Key: InChIKey=PBXFGJKXQNGNJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137098   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50137098 (1-(7-Acetylamino-5,8-dioxo-5,8-dihydro-quinolin-2-...) Show SMILES COC(=O)c1[nH]c(-c2ccc3C(=O)C=C(NC(C)=O)C(=O)c3n2)c2nc3ccccc3c2c1C |t:13| Show InChI InChI=1S/C25H18N4O5/c1-11-19-13-6-4-5-7-15(13)27-23(19)22(29-20(11)25(33)34-3)16-9-8-14-18(31)10-17(26-12(2)30)24(32)21(14)28-16/h4-10,29H,1-3H3,(H,26,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ball State University Curated by ChEMBL					Assay Description Inhibitory activity against HIV-reverse transcriptase (HIV-RT)				J Med Chem 46: 5773-80 (2003) Article DOI: 10.1021/jm0304414 BindingDB Entry DOI: 10.7270/Q2QC02WD
					More data for this Ligand-Target Pair