BDBM50137194 2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-2-yl]-benzylamino}-ethanol::CHEMBL310740

SMILES: OCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1

InChI Key: InChIKey=IUNORHVEZRZFIC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137194   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50137194 (2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...) Show SMILES OCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1 Show InChI InChI=1S/C24H22N4OS/c29-12-11-25-15-16-1-3-17(4-2-16)23-14-22-24(30-23)21(8-10-27-22)28-19-5-6-20-18(13-19)7-9-26-20/h1-10,13-14,25-26,29H,11-12,15H2,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against epidermal growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50137194 (2-{4-[7-(1H-Indol-5-ylamino)-thieno[3,2-b]pyridin-...) Show SMILES OCCNCc1ccc(cc1)-c1cc2nccc(Nc3ccc4[nH]ccc4c3)c2s1 Show InChI InChI=1S/C24H22N4OS/c29-12-11-25-15-16-1-3-17(4-2-16)23-14-22-24(30-23)21(8-10-27-22)28-19-5-6-20-18(13-19)7-9-26-20/h1-10,13-14,25-26,29H,11-12,15H2,(H,27,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against Vascular endothelial growth factor receptor				Bioorg Med Chem Lett 14: 21-4 (2003) BindingDB Entry DOI: 10.7270/Q2FT8KFT
					More data for this Ligand-Target Pair