BDBM50137430 2-[3-Difluoromethyl-5-(4-propyl-phenyl)-pyrazol-1-yl]-5-methanesulfonyl-pyridine::CHEMBL176677

SMILES: CCCc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F

InChI Key: InChIKey=IEOUCXLUAHBHLA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (Canis familiaris)	BDBM50137430 (2-[3-Difluoromethyl-5-(4-propyl-phenyl)-pyrazol-1-...) Show SMILES CCCc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C19H19F2N3O2S/c1-3-4-13-5-7-14(8-6-13)17-11-16(19(20)21)23-24(17)18-10-9-15(12-22-18)27(2,25)26/h5-12,19H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (Canis familiaris)	BDBM50137430 (2-[3-Difluoromethyl-5-(4-propyl-phenyl)-pyrazol-1-...) Show SMILES CCCc1ccc(cc1)-c1cc(nn1-c1ccc(cn1)S(C)(=O)=O)C(F)F Show InChI InChI=1S/C19H19F2N3O2S/c1-3-4-13-5-7-14(8-6-13)17-11-16(19(20)21)23-24(17)18-10-9-15(12-22-18)27(2,25)26/h5-12,19H,3-4H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.				Bioorg Med Chem Lett 14: 95-8 (2003) BindingDB Entry DOI: 10.7270/Q25B01WP
					More data for this Ligand-Target Pair