BDBM50137458 1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-5-carboxylic acid::CHEMBL176662

SMILES: OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1

InChI Key: InChIKey=DBWRASORCAABEO-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137458 (1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1 Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against NS5B polymerase of hepatitis C virus				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair
RNA polymerase subunit beta (β-RNAP) (Escherichia coli)	BDBM50137458 (1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1 Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against calf thymus RNA polymerase				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair
Poliovirus type 1 polyprotein (Poliovirus type 1 (strain Mahoney))	BDBM50137458 (1-Cyclohexyl-2-(1H-pyrrol-2-yl)-1H-benzoimidazole-...) Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc[nH]1 Show InChI InChI=1S/C18H19N3O2/c22-18(23)12-8-9-16-15(11-12)20-17(14-7-4-10-19-14)21(16)13-5-2-1-3-6-13/h4,7-11,13,19H,1-3,5-6H2,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against polio virus RNA polymerase				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair