BDBM50137464 1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-carboxylic acid [2-(3,4-dimethoxy-phenyl)-ethyl]-amide::CHEMBL178076::N-(3,4-dimethoxyphenethyl)-1-cyclohexyl-2-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamide

SMILES: COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC

InChI Key: InChIKey=CLLIKRHLEHADNX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50137464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50137464 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C29H32N4O3/c1-35-26-14-11-20(18-27(26)36-2)15-17-31-29(34)21-12-13-25-24(19-21)32-28(23-10-6-7-16-30-23)33(25)22-8-4-3-5-9-22/h6-7,10-14,16,18-19,22H,3-5,8-9,15,17H2,1-2H3,(H,31,34)	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against NS5B polymerase of hepatitis C virus				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus (HCV))	BDBM50137464 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C29H32N4O3/c1-35-26-14-11-20(18-27(26)36-2)15-17-31-29(34)21-12-13-25-24(19-21)32-28(23-10-6-7-16-30-23)33(25)22-8-4-3-5-9-22/h6-7,10-14,16,18-19,22H,3-5,8-9,15,17H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Wollongong Curated by ChEMBL					Assay Description Inhibitory concentration against hepatitis C virus polymerase				J Med Chem 48: 1-20 (2005) Article DOI: 10.1021/jm0400101 BindingDB Entry DOI: 10.7270/Q2XP75Q1
					More data for this Ligand-Target Pair
Poliovirus type 1 polyprotein (Poliovirus type 1 (strain Mahoney))	BDBM50137464 (1-Cyclohexyl-2-pyridin-2-yl-1H-benzoimidazole-5-ca...) Show SMILES COc1ccc(CCNC(=O)c2ccc3n(C4CCCCC4)c(nc3c2)-c2ccccn2)cc1OC Show InChI InChI=1S/C29H32N4O3/c1-35-26-14-11-20(18-27(26)36-2)15-17-31-29(34)21-12-13-25-24(19-21)32-28(23-10-6-7-16-30-23)33(25)22-8-4-3-5-9-22/h6-7,10-14,16,18-19,22H,3-5,8-9,15,17H2,1-2H3,(H,31,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim (Canada) Ltd Curated by ChEMBL					Assay Description Inhibitory activity against polio virus RNA polymerase				Bioorg Med Chem Lett 14: 119-24 (2003) BindingDB Entry DOI: 10.7270/Q21J9968
					More data for this Ligand-Target Pair