BDBM50137653 CHEMBL3753334

SMILES: CN1CCN(CC1)c1nc(NCc2ccc(F)cc2)nc-2c1CCc1ccccc-21

InChI Key: InChIKey=ZAAKGSGSFGONCJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50137653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Homo sapiens (Human))	BDBM50137653 (CHEMBL3753334) Show SMILES CN1CCN(CC1)c1nc(NCc2ccc(F)cc2)nc-2c1CCc1ccccc-21 Show InChI InChI=1S/C24H26FN5/c1-29-12-14-30(15-13-29)23-21-11-8-18-4-2-3-5-20(18)22(21)27-24(28-23)26-16-17-6-9-19(25)10-7-17/h2-7,9-10H,8,11-16H2,1H3,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]mepyramine from human histamine 1 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50137653 (CHEMBL3753334) Show SMILES CN1CCN(CC1)c1nc(NCc2ccc(F)cc2)nc-2c1CCc1ccccc-21 Show InChI InChI=1S/C24H26FN5/c1-29-12-14-30(15-13-29)23-21-11-8-18-4-2-3-5-20(18)22(21)27-24(28-23)26-16-17-6-9-19(25)10-7-17/h2-7,9-10H,8,11-16H2,1H3,(H,26,27,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universit£t Erlangen-N£rnberg Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation counting				Bioorg Med Chem Lett 26: 292-300 (2016) BindingDB Entry DOI: 10.7270/Q2Z03B0K
					More data for this Ligand-Target Pair