BDBM50138143 CHEMBL3753160

SMILES: Cn1c(cnc1-c1ccc(cc1)C(N)=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=SACWHTSZGSZIFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50138143 (CHEMBL3753160) Show SMILES Cn1c(cnc1-c1ccc(cc1)C(N)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H14ClN3O/c1-21-15(11-6-8-14(18)9-7-11)10-20-17(21)13-4-2-12(3-5-13)16(19)22/h2-10H,1H3,(H2,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human MAP4K4 catalytic domain in presence of 10 uM ATP (Km) by FRET assay				ACS Med Chem Lett 6: 1128-33 (2015) BindingDB Entry DOI: 10.7270/Q2028TC6
					More data for this Ligand-Target Pair