BDBM50138441 2-(hydroxymethyl)-4-(5-(4-(methylthio)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide::2-Hydroxymethyl-4-[5-(4-methylsulfanyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide::CHEMBL357002

SMILES: CSc1ccc(cc1)-c1cc(nn1-c1ccc(c(CO)c1)S(N)(=O)=O)C(F)(F)F

InChI Key: InChIKey=RJTNBPZVAKKVNU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50138441 (2-(hydroxymethyl)-4-(5-(4-(methylthio)phenyl)-3-(t...) Show SMILES CSc1ccc(cc1)-c1cc(nn1-c1ccc(c(CO)c1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S2/c1-28-14-5-2-11(3-6-14)15-9-17(18(19,20)21)23-24(15)13-4-7-16(29(22,26)27)12(8-13)10-25/h2-9,25H,10H2,1H3,(H2,22,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirus				Bioorg Med Chem Lett 14: 499-504 (2003) BindingDB Entry DOI: 10.7270/Q280522Q
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50138441 (2-(hydroxymethyl)-4-(5-(4-(methylthio)phenyl)-3-(t...) Show SMILES CSc1ccc(cc1)-c1cc(nn1-c1ccc(c(CO)c1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C18H16F3N3O3S2/c1-28-14-5-2-11(3-6-14)15-9-17(18(19,20)21)23-24(15)13-4-7-16(29(22,26)27)12(8-13)10-25/h2-9,25H,10H2,1H3,(H2,22,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Discovery Research-Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesicles				Bioorg Med Chem Lett 14: 499-504 (2003) BindingDB Entry DOI: 10.7270/Q280522Q
					More data for this Ligand-Target Pair