null

SMILES: CN(C)CCC#Cc1cccnc1

InChI Key: InChIKey=SGURIVLPISZAAK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50138494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50138494 (CHEMBL150893 | Dimethyl-(4-pyridin-3-yl-but-3-ynyl...) Show SMILES CN(C)CCC#Cc1cccnc1 Show InChI InChI=1S/C11H14N2/c1-13(2)9-4-3-6-11-7-5-8-12-10-11/h5,7-8,10H,4,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Affinity to alpha-4-beta-2 AChR				Bioorg Med Chem Lett 16: 2013-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.073 BindingDB Entry DOI: 10.7270/Q2WD41TH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50138494 (CHEMBL150893 | Dimethyl-(4-pyridin-3-yl-but-3-ynyl...) Show SMILES CN(C)CCC#Cc1cccnc1 Show InChI InChI=1S/C11H14N2/c1-13(2)9-4-3-6-11-7-5-8-12-10-11/h5,7-8,10H,4,9H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards nicotinic acetylcholine receptor alpha4-beta2 from rat brain homogenates				Bioorg Med Chem Lett 14: 523-6 (2003) BindingDB Entry DOI: 10.7270/Q20P117F
					More data for this Ligand-Target Pair