BDBM50138676 6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-cyclopentyloxy-5-isopropoxy-phenyl)-amide::CHEMBL418839

SMILES: CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1

InChI Key: InChIKey=GKFHRQMCFNIZHA-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin-1 (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against porcine trypsin was determined.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity to human urokinase-type plasminogen activator (microPa).				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Tissue-type plasminogen activator (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	844	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human Tissue type plasminogen activator.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	966	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human plasmin.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against human plasma kallikrein.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50138676 (6-Carbamimidoyl-naphthalene-2-carboxylic acid (3-c...) Show SMILES CC(C)Oc1cc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc(OC2CCCC2)c1 Show InChI InChI=1S/C26H29N3O3/c1-16(2)31-23-13-21(14-24(15-23)32-22-5-3-4-6-22)29-26(30)20-10-8-17-11-19(25(27)28)9-7-18(17)12-20/h7-16,22H,3-6H2,1-2H3,(H3,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.16E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity against human alpha thrombin.				J Med Chem 47: 303-24 (2004) Article DOI: 10.1021/jm0300072 BindingDB Entry DOI: 10.7270/Q2BR8RMH
					More data for this Ligand-Target Pair