Found 6 hits for monomerid = 50138983 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Rattus norvegicus (rat)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwestern University
Curated by ChEMBL
| Assay Description Inhibitory activity against neuronal nitric oxide synthase (nNOS) |
J Med Chem 47: 703-10 (2004)
Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description Inhibitory concentration against human endothelial nitric oxide synthase expressed in Sf-9 cells |
Bioorg Med Chem Lett 15: 2881-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description Inhibitory concentration against human neuronal nitric oxide synthase expressed in Sf-9 cells |
Bioorg Med Chem Lett 15: 2881-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 |
More data for this Ligand-Target Pair | |
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
(Homo sapiens (Human)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas
| Assay Description Inhibition assay using DDAH-1 and nNOS. |
Biochemistry 48: 8624-35 (2009)
Article DOI: 10.1021/bi9007098 BindingDB Entry DOI: 10.7270/Q29C6W1P |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50138983
((S)-2-Amino-5-(2-methyl-isothioureido)-pentanoic a...)Show InChI InChI=1S/C7H15N3O2S/c1-13-7(9)10-4-2-3-5(8)6(11)12/h5H,2-4,8H2,1H3,(H2,9,10)(H,11,12)/t5-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description Inhibitory concentration against human inducible nitric oxide synthase expressed in Sf-9 cells |
Bioorg Med Chem Lett 15: 2881-5 (2005)
Article DOI: 10.1016/j.bmcl.2005.03.078 BindingDB Entry DOI: 10.7270/Q2PK0FP1 |
More data for this Ligand-Target Pair | |