BDBM50139351 2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethanamine::CHEMBL158402::[2-(6-Cyclohexyl-pyridin-2-ylsulfanyl)-ethyl]-dimethyl-amine
SMILES: CN(C)CCSc1cccc(n1)C1CCCCC1
InChI Key: InChIKey=QPILPLUOWCUQIQ-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ... | Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans Curated by ChEMBL | Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells | Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 1A receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in HeL... | Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 2A receptor by the displacement of [3H]-Ketanserin radioligand from the cloned receptor expressed ... | Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50139351 (2-(6-cyclohexylpyridin-2-ylthio)-N,N-dimethylethan...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human dopamine receptor D2 by the displacement of [3H]-Spiperone radioligand from the cloned receptor expressed in CHO cells | Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS | |||||||||||
More data for this Ligand-Target Pair |