BDBM50139640 CHEMBL165272::N-4-Substituted-benzyl-N'-tert-butylbenzyl thiourea derivative::N-benzyl-4-sulfamide-N'-(4-tert-butylbenzyl)thiourea

SMILES: CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(N)(=O)=O)cc2)cc1

InChI Key: InChIKey=NWVSMWBHUXOVRR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50139640   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vanilloid receptor (Rattus norvegicus (rat))	BDBM50139640 (CHEMBL165272 | N-4-Substituted-benzyl-N'-tert-buty...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(N)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)16-8-4-14(5-9-16)12-21-18(26)22-13-15-6-10-17(11-7-15)23-27(20,24)25/h4-11,23H,12-13H2,1-3H3,(H2,20,24,25)(H2,21,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro binding affinity for rat TRPV1 expressed in CHO cells using [3H]-RTX				Bioorg Med Chem Lett 15: 4136-42 (2005) Article DOI: 10.1016/j.bmcl.2005.06.009 BindingDB Entry DOI: 10.7270/Q23B5ZN0
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus-Rattus norvegicus (rat))	BDBM50139640 (CHEMBL165272 | N-4-Substituted-benzyl-N'-tert-buty...) Show SMILES CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(N)(=O)=O)cc2)cc1 Show InChI InChI=1S/C19H26N4O2S2/c1-19(2,3)16-8-4-14(5-9-16)12-21-18(26)22-13-15-6-10-17(11-7-15)23-27(20,24)25/h4-11,23H,12-13H2,1-3H3,(H2,20,24,25)(H2,21,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.				Bioorg Med Chem Lett 14: 787-91 (2004) BindingDB Entry DOI: 10.7270/Q2R213KC
					More data for this Ligand-Target Pair