BDBM50140083 CHEMBL3752210

SMILES: N[C@@H](CCN(Cc1ccccc1OCc1ccccc1F)Cc1ccccc1OCc1ccccc1F)C(O)=O

InChI Key: InChIKey=KQUJLMQZLYSIQA-LJAQVGFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral amino acid transporter B(0) (Homo sapiens (Human))	BDBM50140083 (CHEMBL3752210) Show SMILES N[C@@H](CCN(Cc1ccccc1OCc1ccccc1F)Cc1ccccc1OCc1ccccc1F)C(O)=O |r| Show InChI InChI=1S/C32H32F2N2O4/c33-27-13-5-1-11-25(27)21-39-30-15-7-3-9-23(30)19-36(18-17-29(35)32(37)38)20-24-10-4-8-16-31(24)40-22-26-12-2-6-14-28(26)34/h1-16,29H,17-22,35H2,(H,37,38)/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting				Bioorg Med Chem Lett 26: 1044-7 (2016) BindingDB Entry DOI: 10.7270/Q2MC91V1
					More data for this Ligand-Target Pair
Amino acid transporter (Rattus norvegicus)	BDBM50140083 (CHEMBL3752210) Show SMILES N[C@@H](CCN(Cc1ccccc1OCc1ccccc1F)Cc1ccccc1OCc1ccccc1F)C(O)=O |r| Show InChI InChI=1S/C32H32F2N2O4/c33-27-13-5-1-11-25(27)21-39-30-15-7-3-9-23(30)19-36(18-17-29(35)32(37)38)20-24-10-4-8-16-31(24)40-22-26-12-2-6-14-28(26)34/h1-16,29H,17-22,35H2,(H,37,38)/t29-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting				Bioorg Med Chem Lett 26: 1044-7 (2016) BindingDB Entry DOI: 10.7270/Q2MC91V1
					More data for this Ligand-Target Pair