BDBM50140122 CHEMBL3754053
SMILES: Cc1cccc(COc2ccccc2CN(CC[C@H](N)C(O)=O)Cc2ccccc2OCc2cccc(C)c2)c1
InChI Key: InChIKey=YGKNVAAMULVFNN-HKBQPEDESA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amino acid transporter (Rattus norvegicus) | BDBM50140122 (CHEMBL3754053) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of ASCT2-mediated glutamine transport in rat C6 cells using [3H]-glutamine after 15 mins by scintillation counting | Bioorg Med Chem Lett 26: 1044-7 (2016) BindingDB Entry DOI: 10.7270/Q2MC91V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral amino acid transporter B(0) (Homo sapiens (Human)) | BDBM50140122 (CHEMBL3754053) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of ASCT2 (unknown origin) | Eur J Med Chem 163: 215-242 (2019) Article DOI: 10.1016/j.ejmech.2018.11.066 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutral amino acid transporter B(0) (Homo sapiens (Human)) | BDBM50140122 (CHEMBL3754053) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Inhibition of ASCT2-mediated glutamine transport in human HEK293 cells using [3H]-glutamine after 15 mins by scintillation counting | Bioorg Med Chem Lett 26: 1044-7 (2016) BindingDB Entry DOI: 10.7270/Q2MC91V1 | |||||||||||
More data for this Ligand-Target Pair |