BDBM50140400 2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid [2-fluoro-4-(2-methyl-imidazol-1-yl)-phenyl]-amide::CHEMBL282459

SMILES: Cc1cc(C(=O)Nc2ccc(cc2F)-n2ccnc2C)n(n1)-c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=MHKOQJZTWPJGGJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140400 (2-(6-Chloro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)-n2ccnc2C)n(n1)-c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H19ClFN5O/c1-15-11-24(32(30-15)21-6-4-17-12-19(26)5-3-18(17)13-21)25(33)29-23-8-7-20(14-22(23)27)31-10-9-28-16(31)2/h3-14H,1-2H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human Coagulation factor X				Bioorg Med Chem Lett 14: 1221-7 (2004) Article DOI: 10.1016/j.bmcl.2003.12.053 BindingDB Entry DOI: 10.7270/Q2VD6XV5
					More data for this Ligand-Target Pair