BDBM50140421 2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-3-carboxylic acid [4-(azepan-1-yl-imino-methyl)-2-fluoro-phenyl]-amide::CHEMBL278141

SMILES: Cc1cc(C(=O)Nc2ccc(cc2F)C(=N)N2CCCCCC2)n(n1)-c1cc2ccccc2cc1F

InChI Key: InChIKey=PTKUTLFSSIFBAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50140421 (2-(3-Fluoro-naphthalen-2-yl)-5-methyl-2H-pyrazole-...) Show SMILES Cc1cc(C(=O)Nc2ccc(cc2F)C(=N)N2CCCCCC2)n(n1)-c1cc2ccccc2cc1F Show InChI InChI=1S/C28H27F2N5O/c1-18-14-26(35(33-18)25-17-20-9-5-4-8-19(20)15-23(25)30)28(36)32-24-11-10-21(16-22(24)29)27(31)34-12-6-2-3-7-13-34/h4-5,8-11,14-17,31H,2-3,6-7,12-13H2,1H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against human coagulation factor X				Bioorg Med Chem Lett 14: 1229-34 (2004) Article DOI: 10.1016/j.bmcl.2003.12.054 BindingDB Entry DOI: 10.7270/Q2QN6664
					More data for this Ligand-Target Pair